Rash, hives, itching, blistered skin, difficulty breathing, difficulty swallowing, swollen face, throat, or tongue (which can indicate an allergic reaction.Difficulty urinating, blood in the urine, and swollen legs and feet (which can indicate kidney problems).Yellow skin or whites of the eyes, along with dark urine, vomiting, and light-colored stools (which can indicate liver problems).Stomach pain that doesn’t resolve quickly (which can indicate an inflamed pancreas).Bluish tint to lips, nails, fingers, or toes, especially if paired with fatigue or muscle pain, or weakness.Suicidal thoughts, depression, anxiety, and feelings of aggression.In addition, more serious side effects require immediate response from a health care provider. If any of these problems don’t resolve on their own, you should check with a doctor. Difficulties with movement, including jerky movements or lack of coordination.Blurred vision, double vision or unusual eye movement.Other common (and typically mild) side effects include: The most commonly noted side effects of gabapentin are increased appetite and weight gain. Gabapentin is also sold illicitly under the street names Gabbies or Johnnies, with a 300-milligram gabapentin pill selling for as little as 75 cents. It can result in weight gain, since it induces appetite change as well as irritability. In addition, gabapentin is used off-label to treat alcoholism, specifically, symptoms of alcohol withdrawal and cravings. Gabapentin may also be useful for the treatment of sleep problems, as it induces slow-wave sleep, It’s also prescribed to treat hot flashes in menopausal women and those being treated for breast cancer. All three brand-name medications are approved for treatment of postherpetic neuralgia (sometimes known as PHN), which is the nerve pain that follows resolution of a case of shingles, a painful rash that can occur in adults who experienced chickenpox as children.ĭoctors also sometimes prescribe gabapentin off-label to relieve pain, numbness, and tingling resulting from diabetic neuropathy. Horizant is approved for treatment of moderate to severe restless legs syndrome that’s moderate to severe. Neurontin and Gralise are approved for treatment of partial seizures, preventing and controlling these seizures in children 3 and over as well as in adults. The half-life of a standard 300 mg dose of gabapentin is 5–7 hours, meaning half the dose is excreted from the body at this time. As Neurontin, gabapentin is sold in capsules ranging from 100 mg to 400 mg, and in tablet form, it’s available in doses ranging from 300 mg to 800 mg. It’s also available as a generic drug, though as a prescription medication, not available over the counter. It’s a type of anticonvulsant medication that mimics the effects of natural GABA in the body to control neurons in the brain when they become excited, and it’s also effective as a painkiller for certain types of pain.Ĭommercially, gabapentin is sold under the brand names Neurontin, Horizant, and Gralise. It’s a medication for nerve pain that’s used to control seizures and relieve the nerve pain associated with nervous system conditions such as shingles and restless legs syndrome. Gabapentin is an analog of the neurotransmitter GABA, or gamma aminobutyric acid analog. What Is Gabapentin? Understanding Its Use
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